Registered Nurse Salary in Greenville, SC (2026)
Registered Nurses (RNs) provide patient care in hospitals, clinics, schools, and other healthcare settings.
Median Annual Salary
$93,940
in Greenville · BLS OEWS
Real Purchasing Power
$97,203
adjusted for local cost of living
National Rank
#75
among cities with BLS data
Registered Nurses in Greenville
The median annual salary for a Registered Nurse in Greenville, SC is $93,940 per year, according to Bureau of Labor Statistics (BLS) Occupational Employment and Wage Statistics data. This works out to approximately $7,828/month or $45/hour.
Compared to the median across all surveyed cities ($96,980), Greenville pays 3% less than the typical city.
Greenville has a cost of living index of 96.6 (US average = 100), so your salary goes further here than the nominal figure suggests. In inflation-adjusted terms, $93,940 in Greenville is equivalent to $97,203 in a city at the US average cost of living.
BLS wage data is collected at the metropolitan statistical area (MSA) level, so this figure represents the Greenville metro area, not just the city itself.
Top 10 Cities for Registered Nurses by Salary
| # | City | Median Salary |
|---|---|---|
| 1 | Berkeley, CA | $178,450 |
| 2 | San Francisco, CA | $178,450 |
| 3 | Oakland, CA | $178,450 |
| 4 | Sacramento, CA | $163,020 |
| 5 | Folsom, CA | $163,020 |
| 6 | Roseville, CA | $163,020 |
| 7 | Carlsbad, CA | $139,350 |
| 8 | San Diego, CA | $139,350 |
| 9 | Chula Vista, CA | $139,350 |
| 10 | Anaheim, CA | $138,010 |
Source: BLS OEWS · Metro-level data
Other Occupations in Greenville
| Occupation | Median Salary |
|---|---|
| Software Developer | $137,250 |
| Elementary School Teacher | $57,720 |
| Electrician | $63,830 |
| Accountant | $93,550 |
Full cost of living profile for Greenville
See median rent, home values, cost of living index, air quality, and more for Greenville.
Frequently Asked Questions
What is the median Registered Nurse salary in Greenville?
The median annual salary for a Registered Nurse in Greenville, SC is $93,940 per year, according to BLS OEWS data.
How does Greenville Registered Nurse pay compare nationally?
Greenville Registered Nurse pay ($93,940) is 3% below the median across surveyed cities ($96,980).
Does cost of living affect Registered Nurse salaries in Greenville?
Yes. Greenville has a cost of living index of 96.6 (US average = 100). After adjusting for local prices, a $93,940 salary in Greenville has the purchasing power of approximately $97,203 in an average-cost city.
Data last updated: June 1, 2026 · Source: BLS Occupational Employment and Wage Statistics (OEWS) · Methodology