Median rent is 31% lower in St. Louis ($997/mo vs $1,440/mo). Buying is cheaper in St. Louis, where the median home runs $197,500 versus $334,100. Households earn more in Chicago ($77,902 vs $56,160 a year). Taken together, St. Louis is the more affordable choice with a cost index of 95.0 against 102.5 — about 7% lower overall prices. After adjusting income for local prices, a typical paycheck stretches further in Chicago, IL.
Cost of living verdict
St. Louis is 7% cheaper overall
Cost of Living Index: 95.0 in St. Louis vs 102.5 in Chicago (US national average = 100)
City A
Chicago, IL
City B
St. Louis, MO
How much would you need to earn in St. Louis, MO to maintain your standard of living from Chicago, IL?
Equivalent salary in St. Louis, MO
$69,502
You could earn $5,498 less (7% lower) and break even.
Based on BEA Regional Price Parity (cost index) for each metro area. This estimates overall purchasing power; it does not account for taxes or take-home pay differences.
Metric
Chicago
Illinois
St. Louis
Missouri
Population
Median Household Income
Annual
Median Gross Rent
Per month
Median Home Value
Cost of Living Index
US avg = 100
1BR Fair Market Rent
HUD FMR
2BR Fair Market Rent
HUD FMR
3BR Fair Market Rent
HUD FMR
Air Quality Index
Lower = cleaner
Top State Income Tax
Top marginal rate
State Sales Tax
Statewide base rate
Median Age
Years
✓ = better value · Sources: Census ACS, BEA, HUD Fair Market Rents, EPA AirNow, Tax Foundation
Renters will find significantly cheaper housing in St. Louis — median rent of $997/mo versus $1,440/mo in Chicago, a 31% difference. Home buyers face a steeper market in Chicago: the median home is $334,100 versus $197,500 in St. Louis — 41% more expensive.
Metric
Chicago
St. Louis
Software Developer
Registered Nurse
Elementary Teacher
Electrician
Accountant
Higher wage highlighted · BLS OEWS 2023 (metro-level data)
State tax data is not yet available for these cities.
Chicago
Income tax: N/A
Sales tax: N/A
St. Louis
Income tax: N/A
Sales tax: N/A
Chicago has cleaner air on average: 31.0 AQI (Good) compared to 33.0 AQI (Good) in the other city. Lower AQI means cleaner, healthier air.
Pick St. Louis if you prioritize lower overall cost of living (index 95.0 vs 102.5).
Pick Chicago if you prioritize higher median household income ($77,902/yr).
Pick St. Louis if you prioritize cheaper rent ($997/mo median).
St. Louis is cheaper overall, with a cost of living index of 95.0 versus 102.5 (US average = 100). That means prices run about 7% lower in St. Louis.
Median rent is $1,440/mo in Chicago, IL and $997/mo in St. Louis, MO. St. Louis, MO has the lower rent by about 31%.
Median household income is $77,902 in Chicago, IL and $56,160 in St. Louis, MO. Chicago, IL has the higher median income. Note that BLS occupational wages in the table above show wages for specific jobs.
Chicago, IL has better air quality on average: 31.0 AQI versus 33.0 AQI. Both are EPA AirNow annual averages; lower is better.
State tax data is not yet available for one or both cities.
To maintain the same purchasing power, a salary of $100,000 in Chicago, IL is equivalent to roughly $92,669 in St. Louis, MO (using the BEA Regional Price Parity ratio). Use the salary calculator above for any income amount.
Data last updated: June 1, 2026 · Sources: US Census ACS, BEA RPP, BLS OEWS, HUD FMR, EPA AirNow, Tax Foundation · Methodology